Is a reproduction number of one a threshold for Plasmodium falciparum malaria elimination?
نویسندگان
چکیده
منابع مشابه
Basic reproduction number for the transmission of Plasmodium vivax malaria.
The possibility of relapse is introduced into a mathematical model for the transmission of Plasmodium vivax malaria. In the model, the human population is divided into four classes: susceptible, infected, dormant and recovered. Loss of immunity by individuals in the recovered class moves these individuals back into the susceptible class. Two equilibrium states are found, a disease-free state an...
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Background: Cerebral malaria (CM) is one of the major causes of death in African populations infected with Plasmodium falciparum. Only 1% of infected subjects develop CM. The reasons for these differences are not fully understood, but it is likely that the host humoral response against blood-stage antigens plays a role in protection from malaria, although the precise targets and mechanisms medi...
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Calls for the eradication of malaria require the development of global and regional strategies based on a strong and consistent evidence base. Evidence from the previous global malaria eradication program and more recent transborder control campaigns have shown the importance of accounting for human movement in introducing infections to areas targeted for elimination. Here, census-based migrati...
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New York City is a multicultural city where people of different ethnicities and backgrounds from all over the world live together. Of the different ethnicities, it is home to a large population of Western African immigrants. This case report is that of an elderly female of Western African descent presenting to Lincoln Hospitals Emergency Department with fevers and fatigue.The patients travel hi...
متن کاملPlasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission.
Efficient transmission of Plasmodium species between humans and Anopheles mosquitoes is a major contributor to the global burden of malaria. Gametocytogenesis, the process by which parasites switch from asexual replication within human erythrocytes to produce male and female gametocytes, is a critical step in malaria transmission and Plasmodium genetic diversity. Nothing is known about the path...
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ژورنال
عنوان ژورنال: Malaria Journal
سال: 2016
ISSN: 1475-2875
DOI: 10.1186/s12936-016-1437-9